Coagulation factors and the increased risk of stroke in nonvalvular atrial fibrillation.

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Coagulation factors and the increased risk of stroke in nonvalvular atrial fibrillation.

We studied whether hemostatic abnormalities contribute to the increased risk of stroke in patients with nonvalvular atrial fibrillation. Hemostatic function was studied in four age-matched groups: 20 patients with nonvalvular atrial fibrillation and a previous ischemic stroke, 20 patients with nonvalvular atrial fibrillation without a previous stroke, 20 stroke patients with sinus rhythm, and 4...

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Nonvalvular Atrial Fibrillation and Stroke

Cardioembolism, responsible for approximately one-third of cerebral infarctions in Japan, causes serious cerebral infarction with poor prognosis. Nonvalvular atrial fibrillation (NVAF) is the most important cause of cardioembolism. Both the occurrence of NVAF and the frequency of its progression to cerebral infarction increase with age. Timely introduction of warfarin depending on the presence ...

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Nonvalvular atrial fibrillation and stroke: a review.

Nonvalvular atrial fibrillation accounts for more than thirty percent of all strokes above the age of sixty years. The use of anticoagulants for the primary prevention of stroke has been a controversial issue for a long time. New data has emerged which clarifies some of these issues and helps in selecting patients who are at a higher risk of stroke.

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Amiodarone Use Is Associated With Increased Risk of Stroke in Patients With Nonvalvular Atrial Fibrillation

Atrial fibrillation (AF), the most common sustained arrhythmia requiring treatment worldwide, is one of the major causes of ischemic stroke. Although amiodarone is commonly used for rhythm control in AF, its relationship with stroke has rarely been addressed.We evaluated 16,091 patients who were diagnosed with AF (Classification of Diseases, 9th Revision, Clinical Modification [ICD-9-CM] 427.31...

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Prothrombotic activity is increased in patients with nonvalvular atrial fibrillation and risk factors for embolism.

STUDY OBJECTIVES The aim of this study was to investigate whether risk factors for embolism would promote thrombus formation in patients with nonvalvular atrial fibrillation (NVAF). METHODS Hemostatic markers for platelet activity (ie, platelet factor-4 and beta-thromboglobulin [TG]), thrombotic status (ie, prothombin fragments 1 and 2), and fibrinolytic status (ie, d-dimer) were determined i...

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ژورنال

عنوان ژورنال: Stroke

سال: 1990

ISSN: 0039-2499,1524-4628

DOI: 10.1161/01.str.21.1.47